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Department of Pharmaceutical Pathophysiology

Faculty of Pharmacy

EMPLOYEES

Head:

Prof. Dr. Habil. Iwona Inkielewicz-Stępniak

Prof. Dr. Habil. Iwona Inkielewicz-Stępniak

E-mail:iwona.inkielewicz-stepniak@gumed.edu.pl
Direct number:58 349 15 16 ext. 1516

I am a graduate of the Faculty of Pharmacy at the Medical University of Gdańsk (GUMed), Head of the Department of Pharmaceutical Pathophysiology, and Deputy Director of the First Doctoral School at GUMed. I completed two postdoctoral research fellowships at Trinity College Dublin, where I conducted studies on the pharmacological activity of new aspirin analogues, as well as on nanopharmacology and nanotoxicology in vitro. My scientific interests focus on experimental nanomedicine, platelet pharmacology, studies on platelet–cancer cell interactions and the role of platelets in cancer metastasis, as well as research aimed at developing targeted therapies for pancreatic cancer. I am the principal investigator of several research projects funded by the National Science Centre (NCN), including OPUS (evaluation of the potential anticancer activity of new analogues of the opioid growth factor in pancreatic cancer therapy), HARMONIA (assessment of the antithrombotic and antiplatelet effects of functionalized silver nanoparticles), and OPUS LAP (investigation of the potential use of NK cells and graphene oxide nanoparticles in the immunotherapy of pancreatic ductal adenocarcinoma). I also serve as the project leader (on behalf of our university within a scientific consortium) in the European Horizon Programme grant PRECODE, focused on developing a three-dimensional pancreatic cancer model based on patient-derived organoids, as well as in the STER NAWA project supporting the internationalization of the doctoral school. In addition, I am a scientific supervisor in three PRELUDIUM grants and five internal university grants under the Young Creator of Science program. For the past four years, I have been included among the prestigious top 2% of the world’s most influential scientists. I collaborate with Trinity College Dublin, University Hospital Erlangen, the University of Saskatchewan, the University of Janina, the University of Milan, the Luxembourg Institute of Health, Gdańsk University of Technology, the University of Gdańsk, and the University of Warsaw. I have supervised seven completed PhD dissertations and am currently supervising four ongoing ones. One of my doctoral students defended— as the first at our university— a PhD thesis in experimental nanomedicine while still a sixth-year medical student, conducting research as part of a student scientific society project. I also serve as a reviewer of doctoral and habilitation theses, as well as in proceedings for the conferment of the title of professor.

Assistant Professors:

Katarzyna Adamiak-Nikolouzou, Ph.D.

Katarzyna Adamiak-Nikolouzou, Ph.D.

E-mail:katarzyna.adamiak@gumed.edu.pl
Direct number:58 349 15 18 ext. 1518

My scientific research is focused on the antitumor potential of innovative substances, their modifications, and functionalization, with special emphasis on their potential application in malignant melanoma treatment. Currently, I am cooperating with The Center of Innovative Psoriasis and Atopic Dermatitis Treatment and Preparation for Biological Treatment. My scientific interests are as follows: immuno-oncology challenges, pathophysiology of autoimmune diseases, and dermatology. During my industrial PhD studies, which ended with a patent application, at Nicolaus Copernicus University in Torun, as a result of cooperation with the University of Fribourg in Switzerland and the University of Genoa, Italy – I received an Excellence Award for our team at the International Exhibition of Inventions and Technology InnoWings (2023).

Damian Flis, Ph.D.

Damian Flis, Ph.D.

E-mail:damian.flis@gumed.edu.pl
Direct number:58 349 15 17 ext. 1517

Assistant professor at the Department of Pharmaceutical Pathophysiology.
The topic of his doctoral dissertation was the influence of swimming on the concentration
of mitochondrial cholesterol and energy metabolism in conditions of oxidative stress. The main scientific interests of the doctor include research on energy and free radical metabolism
and mitochondrial function in conditions of health, physical exercise, and pathology development.
At present, Mr. Damian works on scientific projects related to the search of the mechanism responsible for changes in the mitochondrial cholesterol level under exercise condition-
the role of Caveolin-1 protein, and molecular mechanism of the protective effect of swimming training on skeletal muscle atrophy and the course of amyotrophic lateral sclerosis (ALS).

Senior Assistant:

Klaudia Kubiak, Ph.D.

Klaudia Kubiak, Ph.D.

E-mail:klaudia.kubiak@gumed.edu.pl

I am a biomedical scientist specializing in oncology and neurobiology. I obtained my PhD in molecular medicine from the University of Göttingen, where I studied the impact of the H3.3K27M mutation on the function of CBP/p300 and BET family proteins in pediatric gliomas (DIPG). My research focuses on epigenetic mechanisms in cancer and the investigation of new therapeutic strategies. Currently, I am conducting research on targeted therapies for pancreatic ductal adenocarcinoma (PDAC) and brain tumors, utilizing epigenetic inhibitors, PROTACs, and nanoparticle-based drug delivery systems. The goal of my work is to develop innovative therapeutic strategies that can be applied in cancer treatment, contributing to improved therapy efficacy and the quality of life of oncology patients.

Assistants:

Karol Steckiewicz, Ph.D.

Karol Steckiewicz, Ph.D.

E-mail:karol.steckiewicz@gumed.edu.pl

My scientific interests focus on nanotechnology with particular emphasis on research in the field of nanomedicine. In the current projects, we are focusing on assessing the role of noble metal nanoparticles as drug carriers that can potentially be used in periodontitis and inflammatory bowel diseases. We study the anti-inflammatory and antimicrobial properties of nanoparticles as well as the synergistic effects of nanoparticles and drugs. My clinical interests focus on anaesthesiology and intensive care

Senior Specialists:

Shaoshan Mai, MPharm.

Shaoshan Mai, MPharm.

E-mail:shaoshan.mai@gumed.edu.pl
Direct number:58 349 15 17

I did some research on stem cells and autoimmune disease during my study of Master degree in China. After graduation, I worked as a research assistant to investigate lung cancer, hepatic cancer and pancreatic cancer in Sun Yan-sen University. In 2018, I moved to Germany and worked with gastric cancer induced by helicobacter pylori(H. pylori) infection. Currently, I am an ESR in EU Horizon 2020 Marie Skłodowska-Curie Program(PancREatic Cancer OrganoiDs rEsearch, PRECODE) under the supervision of Prof. Iwona Inkielewicz-Stępniak. I cooperate with colleagues in our lab to develop three-dimensional model of pancreatic cancer ( Patient-Derived Organoids ), set up co-culture system in organoids with platelets, organoids with human umbilical vein endothelial cells(HUVECs). To investigate the crosstalk between platelets or HUVECs and organoids, and effect of chemical drugs, nanoparticle drugs on pancreatic cancer treatment are part of my PhD study project. My scientific interests are tumor treatment, autoimmune disease and nanoparticle medicines.

Olga Tovchiga, Ph.D.

Olga Tovchiga, Ph.D.

E-mail:olga.tovchiga@gumed.edu.pl
Direct number:58 349 15 17 ext. 1517

I Graduated of Clinical Pharmacy, obtained Ph.D. degree and Doctorate degree in the field of experimental pharmacology at the National University of Pharmacy (Kharkiv, Ukraine). My primaryscientific interests are focused on pharmacology of purine metabolism regulation and water- salt exchange.I possess an experience in verification and in-depth study of nephrotropic, metabolic (especially, anti-diabetic), neurotropic, psychotropic, organoprotective effectsof natural and synthetic agents, acute and chronic toxicity determination, as well as basic skills of in vitro techniques. My background in teaching pharmacology and toxicology facilitates comprehension during the studies of biological systems.

Doctoral Students:

Damian Drążewski, M.D.

Damian Drążewski, M.D.

E-mail:damian.stom@gmail.com

I am a graduate of the Faculty of Medicine at the Medical University of Poznań. My research interests focus on the molecular mechanisms related to the aging process of the skin and the use of tissue stimulants in anti-aging treatments. The second area of my research is to determine how collagen stimulators work at the cellular level and to assess their impact on protection against the harmful effects of UV radiation on skin cells.

Swathy Krishna Reghukumar, MPharm.

Swathy Krishna Reghukumar, MPharm.

E-mail:swathy.reghukmar@gumed.edu.pl

I graduated in Pharmacology from JSS Academy of Higher Education and Research (Mysore, India). My current research topic under the supervision of Prof. Dr. Iwona Inkielewicz-Stępniak and prof. Elzbiety Megiel from Warsaw University involves evaluation of anti-cancer activity of novel functionalized metal nanoparticles in breast cancer therapy. This involves the synthesis of functionalized metal nanoparticles and evaluation of their potential for selective cytotoxic action against cancer cells.

Zosia Skalska, MPharm.

Zosia Skalska, MPharm.

E-mail:zosia.skalska@gumed.edu.pl

I hold a Master of Pharmacy degree from the Medical University of Gdańsk. I completed my master’s thesis in Belgium at Ghent University, in the Laboratory of Drug Quality & Registration, Faculty of Pharmaceutical Sciences, focusing on the use of polar-embedded columns in bioanalysis. I completed an internship at Polfa Tarchomin in Warsaw in the microbiology and preformulation departments. I have worked in both community and hospital pharmacy. Currently, I am pursuing a PhD at the Department of Pharmaceutical Pathophysiology under the supervision of prof. dr hab. Iwona Inkielewicz-Stępniak. My research focuses on smart plasmonic–magnetic nanohybrids for image-guided targeted cancer therapy, with particular emphasis on breast and pancreatic cancer.

Site update: 28.10.2025
Dominika Fortuna, Iwona Inkielewicz-Stępniak